current projects

The courtship ritual of Drosophila melanogaster involves singing, tapping, and copulation.
 

1.MOLECULAR MODULATORS OF PHEROMONE PERCEPTION

We recently showed that chemosensory perception can have long term effects on fertility (Ng et al., Nat Comm, 2015). We are attempting to identify the downstream modulators that mediate this effect.

2.CHEMICAL DIVERSITY OF NATIVE HAWAIIAN DROSOPHILA

The Hawaiian Drosophila clade exhibit spectacular ecological and behavioral variation. We seek to characterize the chemical diversity of Hawaiian drosophilid cuticular lipids and pheromones using mass spectrometry and the influence of environmental and social factors. Transcriptomics will be used to examine the underlying biosynthetic pathways. 


collaborators

Mass spectrometry images of various lipid species throughout whole body sections of Drosophila (see Niehoff et al., 2014).

Stephen Blanksby (Queensland University of Technology, Australia): Application of ozone- and collision-induced dissociation for structural characterization of lipid pheromones.

Robert Chip Cody (JEOL USA): Chemical profiling of biological tissue by Direct Analysis in Real Time mass spectrometry (DART MS).

Klaus Dreisewerd (University of Münster, Germany): Mass spectrometry imaging of Drosophila lipids and pheromones; chemical profiling of live insects.

Kenji Mori (University of Tokyo, Japan): Chemical synthesis of insect pheromones

 

We welcome collaborations with researchers interested in mass spectrometry instrumentation, organic synthesis, and the chemical ecology of other organisms.