• Cetraro N, Cody RB, Yew JY*. 2019. Carbon-carbon double bond position elucidation in fatty acids using ozone-coupled direct analysis in real time mass spectrometry. Analyst, in press.

  • Schwartzman JA, Lynch JB, Flores-Ramos S, Zhou L, Apicella MA, Yew JY, Ruby EG. 2019. Acidic pH promotes lipopolysaccharide modification and alters colonization in a bacteria-animal mutualism. Mol Micro, in press.

  • Massey JH, Akiyama N, Bien T, Dreisewerd K, Wittkopp PJ*, Yew JY*, Takahashi A*. 2019. Pleitropic effects of bony and tan on pigmentation and cuticular hydrocarbon composition in Drosophila melanogaster. Front Physiol 10: 518.

  • Bien T, Gadau J, Schnapp A, Yew JY, Sievert C, Dreisewerd, K. 2019. Detection of very long chain hydrocarbons by laser mass spectrometry reveals novel species and sex and age-dependent differences in the cuticular profiles of three Nasonia species. Anal Bioanal Chem 411(13): 2981-2993.

  • Franke AA*, Biggs L, Yew JY*, Lai JF. 2019. Areca alkaloids measured from buccal cells using DART-MS serves as accurate biomarkers for areca nut chewing. Drug Test Anal 11(6): 906-911.


  • Selkrig S, Mohammad F, Ng SH, Chua JY, Tumkaya T, Ho J, Chiang YN, Rieger D, Pettersson S, Helfrich-Foerster C, Yew JY*, Claridge-Chang A*. 2018. The Drosophila microbiome has a limited influence on sleep, activity, and courtship behaviors. In press. Sci Rep.

  • Holland BS, Gousy-Leblanc M, Yew JY. 2018. Strangers in the dark: Behavioral and biochemical evidence for trail pheromones in Hawaiian tree snails. Invertebr Biol. In press.

  • Schultzhaus J, Bennett C, Iftikhar H, Yew JY, Mallett J, Carney G. 2018. High fat diet alters Drosophila melanogaster sexual behavior and traits: decreased attractiveness and changes in pheromone profiles. Sci Rep. 8(1): 5387.

  • Hynson NA, Frank KL, Alegado RA, Amend AS, Arif M, Bennett GM, Jani AJ, Medeiros MCI, Mileyko Y, Nelson CE, Nguyen NH, Nigro OD, Prisic S, Shin S, Takagi D, Wilson ST, Yew JY. 2018. Synergy among Microbiota and Their Hosts: Leveraging the Hawaiian Archipelago and Local Collaborative Networks to Address Pressing Questions in Microbiome Research. mSystems 3(2): e00159-17.


  • Poff KE, Stever H, Reil JB, Seabourn P, Ching AJ, Aoki S, Logan M, Michalski JR, Santamaria J, Adams JW, Eiben JA, Yew JY, Ewing CP, Magnacca KN, Bennett GM. 2017.  The Native Hawaiian Insect Microbiome Initiative: A Critical Perspective for Hawaiian Insect Evolution. Insects 8(4): 130-144.

  • Dreisewerd K and Yew JY. 2017. Mass spectrometry imaging goes three dimensional. Nature Methods News & Views. 14(12): 1139-1140.

  • Yew JY and Chung H. 2017. Drosophila as a holistic model for insect pheromone signaling and processing. Curr Opin Insect Sci. 24: 15-20. Review.

  • Hebbar S, Khandelwal A, R J, Hindle SJ, Chiang YN, Yew JY, Sweeney ST, Schwudke D. 2017. Lipid metabolic perturbation is an early-onset phenotype in adult spin mutants: a Drosophila model for lysosomal storage disorders. Mol Biol Cell. 28(26): 3728-3740.


  • Dion E, Monteiro A, and Yew JY. 2016. Phenotypic plasticity in sex pheromone production in Bicyclus anynana butterflies. Sci Rep. 6:39002.

  • Chiang YN, Tan KJ, Chung H, Lavrynenko O, Shevchenko A, and Yew JY. 2016. Steroid Hormone Signaling Is Essential for Pheromone Production and Oenocyte Survival. PLoS Genetics. 12(6): e1006126.

    • Featured in New Scientist, July 2016; Honolulu Star Advertiser, July 2016; Hawai'i Public Radio; KGMB Hawai'i News Now; Wired Jargon Watch

  • Lin HH, Cao DS, Sethi S, Zeng Z, Chin JS, Chakraborty TS, Shepherd AK, Nguyen CA, Yew JY, Su CY, and Wang JW. 2016. Hormonal Modulation of Pheromone Detection Enhances Male Courtship Success. Neuron. 90(6): 1272-1285.

  • Shankar S, Calvert MEK, and Yew JY. 2016. Measuring physiological responses of Drosophila sensory neurons to lipid pheromones using live calcium imaging. J Vis Exp. 110. doi: 10.3791/533922.

  • Marshall DL, Pham HT, Bhujel M, Chin JSR, Yew JY, Mori K, Mitchell TW, and Blanksby SJ. 2016. Sequential collision- and ozone-induced dissociation enables assignment of relative acyl chain position in triacylglycerols. Anal Chem. 88(5): 2685-2693.


  • Ng WC, Chin JSR, Tan KJ, Yew JY. 2015. The fatty acid elongase Bond is essential for Drosophila sex pheromone synthesis and male fertility. Nat Commun. 6: 9263.

  • Reiff T, Jacobson J, Cognigni P, Antonello Z, Ballesta E, Tan KJ, Yew JY, Dominguez M, Miguel-Aliaga I. 2015. Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. Elife. 4: e06930

  • Shankar S, Chua JY, Tan KJ, Calvert ME, Weng R, Ng WC, Mori K, Yew JY. 2015. The neuropeptide tachykinin is essential for pheromone detection in a gustatory neural circuit. Elife. 4: e06914.

  • Yew JY and Chung H. 2015. Insect pheromones: an overview of function, form, and discovery. Prog Lipid Res. 59: 88-105.

  • Vasudevan A, Kumar V, Chiang YN, Yew JY, Cheemadan S, and Vyas A. 2015. Aplha2u-glubulins mediate manipulation of host attractiveness in Toxoplasma gondii – Rattus novergicus association. ISME J. 9(9): 2112-2115.


  • Niehoff AC, Kettling H, Pirkl A, Chiang YN, Dreisewerd K, Yew JY. 2014. Analysis of Drosophila lipids by MALDI-MS imaging. Anal Chem. 86(22): 11086-11092.

  • He Y, Yam C, Pomraning K, Chin JSR, Yew JY, Freitag M, Oliferenko S. 2014. Increase in cellular triacylglycerol content and emergence of large ER-associated lipid droplets in the absence of CDP-DG synthase function. Mol Biol Cell. 25(25): 4083-4095.

  • Araujo DP, Tuan MJM, Yew JY*, Meier R*. 2014. Analysing small insect glands with UV-LDI MS: high-resolution spatial analysis reveals the chemical composition and use of the osmeterium secretion in Themira superba (Sepsidae: Diptera). J Evol Biol. 27(8): 1744-1750.

  • Chin JSR, Ellis SR, Pham HT, Blanksby SJ, Mori K, Koh QL, Etges WJ, Yew JY. 2014. Sex-specific triacylglycerides are widely conserved in Drosophila and mediate mating behavior. eLife 3: e01751.

    • Featured in The Scientist, Editor’s choice in biochemistry, July 2014.

    • Featured in The Naked Scientists (Cambridge University). March 2014 podcast

  • Ng SH, Shankar S, Shikichi Y, Akasaka K, Mori K, and Yew JY. 2014. Pheromone evolution and sexual behavior in Drosophila are shaped by male sensory exploitation of other males. Proc Natl Acad Sci. 111(8): 3056-3061.


  • Gendron C, Kuo TH, Harvanek ZM, Chung BY, Yew JY, Dierick HA, and Pletcher SD. 2013. Drosophila lifespan and physiology are modulated by sexual perception and reward. Science. 343(6170): 544-548.

    • See also commentary in Perspectives: Promislow D and Kaeberlein M. 2014. Chemical Warfare in the Battle of the Sexes. Science. 343: 491-492.

  • Shikichi Y, Shankar S., Yew JY, and Mori K. 2013. Synthesis and Bioassay of the Eight Analogues of Male Pheromone CH503 (3-Acetoxy-11,19-octacosadien-1-ol) of the Fruit Fly Drosophila melanogaster. Biosci Biotechnol Biochem 77(9): 1931-1938.

  • Weng R, Chin J, Yew JY, Bushati N, and Cohen SM. 2013 mir-124 controls male reproductive success in Drosophila. eLife 2: e00640.

  • Chin J, Yew JY. 2013. Sampling, chromatographic purification, and chemical analysis of pheromone molecules: Pheromones in the Fruit Fly. Methods Mol Bio. 1068: 15-27.


  • Fedina TY, Kuo TH, Dreisewerd K, Dierick HA, Yew JY, and Pletcher SD. 2012. Dietary effects on cuticular hydrocarbons and sexual attractiveness in Drosophila. PLoS One 7(12): e49799.

  • Shikichi Y, Akasaka K, Tamogami S, Shankar S, Yew JY, and Mori K. 2012. Pheromone synthesis. Part 250: determination of the stereostructure of CH503, a sex pheromone of male Drosophila melanogaster, as (3R,11Z,19Z)-3-acetoxy-11,19-octacosadien-1-ol by synthesis and chromatographic analysis of its eight isomers. Tetrahedron 68(19): 3750 - 3760.

  • Kuo TH, Fedina TY, Hansen I, Dreisewerd K, Dierick HA, Yew JY, and Pletcher SD. 2012. Insulin signaling mediates sexual attractiveness in Drosophila. PLoS Genetics 8(4): e1002684.

  • Kuo TH, Yew JY, Fedina TY, Dreisewerd D, Dierick HA, Pletcher SD. 2012. Aging modulates cuticular hydrocarbons and sexual attractiveness in Drosophila. J Exp Biol. 215: 814 – 821.

    • See also commentary in Inside JEB: Hager Y. 2012. Old flies lose sex appeal. J Exp Biol. 215: i – ii.


  • Yew JY, Soltwisch J, Pirkl A, Dreisewerd K. 2011. Direct laser desorption ionization of endogenous and exogenous compounds from insect cuticles: practical and methodological aspects. J Amer Soc Mass Spec. 22: 1273 – 1284.

  • Yew JY, Dreisewerd K, de Oliveira CC, Etges WJ. 2011. Male-specific transfer and fine scale spatial differences of newly identified cuticular hydrocarbons and triacylglycerides in aDrosophila species pair. PLoS One. 6(2): e16898.

  • de la Paz Fernández M, Chan YB, Yew JY, Billeter JC, Dreisewerd K, Levine J, Kravitz EA. 2010. Pheromonal and Behavioral Cues Trigger Male-to-Female Aggression in Drosophila.PLoS Biology. 8(11): e1000541.

  • Mori K, Shikichi Y, Shankar S, Yew JY. 2010. Pheromone synthesis. Part 244: Synthesis of the racemate and enantiomers of (11Z, 19Z)-CH503 (3-acetoxy-11,19-octacosadien-1-ol), a new sex pheromone of male Drosophila melanogaster to show its (S)-isomer and racemate as bioactive. Tetrahedron 66(35): 7161-7168.

  • Pirkl A, Dreisewerd K, Yew JY, König S. 2009. Field-based ion generation from microscale emitters on natural and artificial objects for atmospheric pressure mass spectrometry. Anal Bioanal Chem. 397(8): 3311-6.

  • Yew JY, Dreisewerd K, H, Luftmann H, Müthing J, Pohlentz G, Kravitz EA. 2009. A new male sex-pheromone and novel cuticular cues for chemical communication in Drosophila. Curr Biol. 19 (15): 1245 – 1254.

    • See also commentary in Current Biology Dispatch: Levine JD and Millar JG. 2009. Chemical signaling: laser on the fly reveals a new male-specific pheromone. Curr Biol. 19 (15): R653-655.

  • Yew JY, Wang Y, Barteneva N, Dikler S, Kutz-Naber K, Li L, Kravitz EA. 2009. Analysis of neuropeptide expression and localization in adult Drosophila melanogaster central nervous system by affinity cell-capture mass spectrometry. J Proteome Res. 8 (3): 1271-1284.

  • Yew JY, Cody RB, Kravitz EA. 2008. Cuticular hydrocarbon analysis of an awake behaving fly using Direct Analysis in Real Time time-of-flight mass spectrometry. Proc Natl Acad Sci 105 (20): 7135-7140.

  • Yew JY, Davis R, Dikler S, Nanda J, Reinders B, Stretton AO. 2007. Peptide products of the afp-6 gene of the nematode Ascaris suum have different biological actions. J Comp Neurol 502(5):872-882.

  • Yew JY, Kutz KK, Dikler S, Messinger L, Li L, Stretton AO. 2005. Mass spectrometric map of neuropeptide expression in Ascaris suum. J Comp Neurol 488(4):396-413.

  • Yew JY, Dikler S, Stretton AO. 2003. De novo sequencing of novel neuropeptides directly from Ascaris suum tissue using matrix-assisted laser desorption/ionization time-of-flight/time-of-flight. Rapid Commun Mass Spectrom 17(24):2693-2698.

  • Hedrick AV, Perez D, Lichti N, Yew J. 2002. Temperature preferences of male field crickets (Gryllus integer) alter their mating calls. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 188(10):799-805.

  • Gold BG, Yew JY, Zeleny-Pooley M. 1998. The immunosuppressant FK506 increases GAP-43 mRNA levels in axotomized sensory neurons. Neurosci Lett 241(1):25-28.